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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
11.5 DPC

23 matching records from 23 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kit  KIT proto-oncogene receptor tyrosine kinase   (Synonyms: belly-spot, CD117, c-KIT, Dominant white spotting, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Steel Factor Receptor, Tr-kit)
Results  Reference
1*J:238674 Barrett NA, Malouf C, Kapeni C, Bacon WA, Giotopoulos G, Jacobsen SE, Huntly BJ, Ottersbach K, Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016 Jul 26;16(4):1039-54
1J:289362 Di Siena S, Gimmelli R, Nori SL, Barbagallo F, Campolo F, Dolci S, Rossi P, Venneri MA, Giannetta E, Gianfrilli D, Feigenbaum L, Lenzi A, Naro F, Cianflone E, Mancuso T, Torella D, Isidori AM, Pellegrini M, Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Cell Death Dis. 2016 Jul 28;7(7):e2317
1*J:25082 Duttlinger R, Manova K, Berrozpe G, Chu TY, DeLeon V, Timokhina I, Chaganti RS, Zelenetz AD, Bachvarova RF, Besmer P, The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice. Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3754-8
1*J:13166 Duttlinger R, Manova K, Chu TY, Gyssler C, Zelenetz AD, Bachvarova RF, Besmer P, W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis. Development. 1993 Jul;118(3):705-17
1J:173280 Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, Haigh K, Seuntjens E, Umans L, Riedt T, Bogaert P, Haenebalcke L, Berx G, Dzierzak E, Huylebroeck D, Haigh JJ, The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood. 2011 May 26;117(21):5620-30
1J:132880 Gore BB, Wong KG, Tessier-Lavigne M, Stem cell factor functions as an outgrowth-promoting factor to enable axon exit from the midline intermediate target. Neuron. 2008 Feb 28;57(4):501-10
1J:185553 Hari L, Miescher I, Shakhova O, Suter U, Chin L, Taketo M, Richardson WD, Kessaris N, Sommer L, Temporal control of neural crest lineage generation by Wnt/beta-catenin signaling. Development. 2012 Jun;139(12):2107-17
1*J:53322 Hearn CJ, Young HM, Ciampoli D, Lomax AE, Newgreen D, Catenary cultures of embryonic gastrointestinal tract support organ morphogenesis, motility, neural crest cell migration, and cell differentiation. Dev Dyn. 1999 Mar;214(3):239-47
1*J:24542 Hirata T, Kasugai T, Morii E, Hirota S, Nomura S, Fujisawa H, Kitamura Y, Characterization of c-kit-positive neurons in the dorsal root ganglion of mouse. Brain Res Dev Brain Res. 1995 Apr 18;85(2):201-11
1J:213982 Hozumi H, Takeda K, Yoshida-Amano Y, Takemoto Y, Kusumi R, Fukuzaki-Dohi U, Higashitani A, Yamamoto H, Shibahara S, Impaired development of melanoblasts in the black-eyed white Mitf(mi-bw) mouse, a model for auditory-pigmentary disorders. Genes Cells. 2012 Jun;17(6):494-508
1J:169135 Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA, Francis-West P, Irvine KD, Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development. 2011 Mar;138(5):947-57
1J:159348 McMullen NM, Zhang F, Pasumarthi KB, Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system. J Cell Mol Med. 2009 Sep;13(9A):2834-42
1*J:46130 Nakayama A, Nguyen MT, Chen CC, Opdecamp K, Hodgkinson CA, Arnheiter H, Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66
1J:231654 Sanchez-Ferras O, Bernas G, Farnos O, Toure AM, Souchkova O, Pilon N, A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network. Development. 2016 Apr 15;143(8):1363-74
1J:166908 Sasaki T, Mizuochi C, Horio Y, Nakao K, Akashi K, Sugiyama D, Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse. Development. 2010 Dec;137(23):3941-52
1J:114384 Schmidt-Ott KM, Chen X, Paragas N, Levinson RS, Mendelsohn CL, Barasch J, c-kit delineates a distinct domain of progenitors in the developing kidney. Dev Biol. 2006 Nov 1;299(1):238-49
1J:227907 Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL, Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701
1J:63424 Takakura N, Watanabe T, Suenobu S, Yamada Y, Noda T, Ito Y, Satake M, Suda T, A role for hematopoietic stem cells in promoting angiogenesis. Cell. 2000 Jul 21;102(2):199-209
1J:324688 Van Deren DA, De S, Xu B, Eschenbacher KM, Zhang S, Capecchi MR, Defining the Hoxb8 cell lineage during murine definitive hematopoiesis. Development. 2022 Apr 15;149(8):dev200200
1J:123757 Yamada Y, Takakura N, Physiological pathway of differentiation of hematopoietic stem cell population into mural cells. J Exp Med. 2006 Apr 17;203(4):1055-65
1J:165571 Yokomizo T, Dzierzak E, Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010 Nov;137(21):3651-61
1J:269471 Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA, Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos. Elife. 2015 Oct 13;4:e07780
1*J:233748 Yzaguirre AD, Speck NA, Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos. Dev Biol. 2016 Jul 1;415(1):111-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory